Endoplasmicreticulum相关论文
We investigated the mechanisms underlying damage to rat small intestine in heat-and shake-induced stress.Eighteen Spragu......
Nuclear-translocation of calreticulin aggravates endoplasmic reticulum stress-associated apoptosis d
Calreticulin (CRT) is a major Ca2+-binding chaperone mainly resident in the endoplasmic reticulum (ER) lumen.Recently,it......
BACKGROUND Genetic factors play an important role in the pathogenesis of diabetic retinopathy(DR).However,while many stu......
Induction of endoplasmic reticulum stress and the modulation of thioredoxin-1 in formaldehyde-induce
Formaldehyde (FA), a common environmental pollutant, has toxic effects on central nervous system.The detailed mechanism ......
Endoplasmic reticulum(ER)stress has been implicated in some types of glomerular and tubular disorders.The objectives of ......
Homocysteine increased ER-mitochondrial coupling with promoting mitochondrial respiration and T cell
Homocysteine (Hcy) is a sulfur-containing non-constitutive amino acid derived from the essential amino acid methionine.N......
A novel mammalian transcription factor SCIRR69 is involved in the activation of brain-derived neurot
The complete cDNA sequence of a novel gene, spinal cord injury and regeneration related gene No.69 (SCIRR69) obtained by......
Normal folding requires that unique conditions be maintained within the ER lumen,and nascent proteins are initially boun......
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Alleviating cataract with Shijueming aqueous extract through inhibiting ROS and endoplasmic reticulu
AIM: To investigate the potential mechanism mediating the protective effects of Shijueming on cataract.METHODS: Eighty r......
Objective To study after BDE-153 exposed, caspase-12 and TMEM132a on the endoplasmic reticulum in the levels of protein ......
γ-glutamyl transpeptidase(GGT),as an important membrane-bound enzyme,possesses excellent optical activity and specific ......
Small Molecular Mimics Modulate Neuron Mitochondria Restoration and Endoplasmic Reticulum Response v
MnSOD is thought to be essential in a series of CNS disorders including Alzheimers disease, Parkinsons disease, stroke a......
An Epidermal Growth Factor Receptor-Targeted and Endoplasmic Reticulum-Localized Organic Photosensit
The endoplasmic reticulum(ER),as the largest organelle in eukaryotic cells,plays complex but pivotal roles in multiple i......
A new endoplasmic reticulum-targeted ratiometric fluorescent probe for imaging of superoxide anion i
Superoxide anion((O2))serves as a precursor of other reactive oxygen species(ROS).Aberrant production or accumulation of......
Recently, we found that high concentration of taxol (70 μM) induced cell death with cytoplasm vacuolization, the typica......
Critical hubs of renal ischemia-reperfusion injury: endoplasmic reticulum-mitochondria tethering com
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Disulfide bonds play important roles in the structure and function of many secretory and membrane proteins.In the endopl......
VAPs,Candidate Proteins Involved in Anchoring the Endoplasmic Reticulum to the Plasma Membrane in Pl
The cortical endoplasmic reticulum (ER) network in plant cells is a highly dynamic structure; its movements are regu......
Olanzapine Induces Inflammation and Immune Response via Activating ER Stress in the Rat Prefrontal C
Objective Antipsychotics,in particular olanzapine,are first-line medications for schizophrenia.The prefrontal cortex(PFC......
目的：探讨靶向蛋白激酶样内质网激酶(protein kinase like endoplasmic reticulum kinase,PERK]基因的小干扰RNA(small interfe......
Revealing HOCl burst from endoplasmic reticulum in cisplatin-treated cells via a ratiometric fluores
The reactive oxygen species(ROS)are tightly associated with endoplasmic reticulum(ER)stress.Thus,the deep and visual ins......
电镜技术的应用使人们对细胞的超微结构有了更深入的了解。各种细胞器的结构以及其病理状况时发生的改变为人们判断疾病的发生提供......
目的观察内质网应激(ERS)相关分子在糖尿病大鼠坐骨神经中的变化，探讨ERS在糖尿病周围神经病变中的作用。方法采用高脂喂养联合腹腔......
目的探讨二十二碳六烯酸(DHA)对食管癌细胞EC9706顺铂(DDP)化疗敏感性的影响及其机制。方法不同药物干预将实验组分为：空白对照组、......
AIM: To determine the pathological characteristics of gastric leiomyoblastoma.METHODS: All tissues were obtained during ......
The molecular mechanism of how hepatocytes maintain cholesterol homeostasis has become much more transparent with the di......
AIM: To study the effects of sense and antisense KAI1genes on the growth and invasion of human hepatocellularcarcinoma (......
目的 研究β-淀粉样蛋白(Aβ25-35)对大鼠海马细胞内质网钙库的影响.方法 将40只成年清洁级雄性SD大鼠按体重随机分为4组,分别为A......
目的 探讨高脂血症对大鼠急性胰腺炎的损伤机制.方法 对高脂饮食SD大鼠和正常饮食SD大鼠均分别予雨蛙肽腹腔注射和牛磺胆酸钠胰管......
目的 通过建立大鼠非酒精性脂肪性肝病(NAFLD)模型,探讨内质网应激(ERS)在NAFLD中的作用.方法 36只雄性SD大鼠分为对照1组(n=8)、......
